CEM-VM1
Definition:
CEM-VM1 is a human T-cell-derived cancer cell line derived from Peripheral blood and associated with Childhood T acute lymphoblastic leukemia and Precursor T-cell acute lymphoblastic leukemia. CEM-VM1 is a resistant derivative of CCRF-CEM selected against Teniposide (VM-26. CEM-VM1 is used as an in vitro model of Childhood T acute lymphoblastic leukemia and Precursor T-cell acute lymphoblastic leukemia to investigate tumor-cell growth, cell survival, and pharmacological response.
References:
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[1]. Beck WT, et al. Pharmacological, molecular, and cytogenetic analysis of "atypical" multidrug-resistant human leukemic cells. Cancer research. 1987;47(20):5455-60. [Content Brief]
[2]. Danks MK, Yalowich JC, Beck WT. Atypical multiple drug resistance in a human leukemic cell line selected for resistance to teniposide (VM-26). Cancer research. 1987;47(5):1297-301. [Content Brief]
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