Chromodomain-helicase-DNA-binding protein 1-like
Definition:
References:
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[1]. Jugal Mohapatra, et al. Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling. Elife. 2021 Dec 7;10:e71502. [Content Brief]
[2]. Luka Bacic, et al. Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome. Elife. 2021 Sep 6;10:e71420. [Content Brief]
[3]. Laura C Lehmann, et al. Mechanistic Insights into Autoinhibition of the Oncogenic Chromatin Remodeler ALC1. Mol Cell. 2017 Dec 7;68(5):847-859.e7. [Content Brief]
[4]. Li Wang, et al. Structural basis of ALC1/CHD1L autoinhibition and the mechanism of activation by the nucleosome. Nat Commun. 2021 Jul 1;12(1):4057. [Content Brief]
[5]. Hari R Singh, et al. A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene. Mol Cell. 2017 Dec 7;68(5):860-871.e7. [Content Brief]
[6]. Dragana Ahel, et al. Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science. 2009 Sep 4;325(5945):1240-3. [Content Brief]
[7]. Laura C Lehmann, et al. Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch. Cell Rep. 2020 Dec 22;33(12):108529. [Content Brief]
[8]. Charlotte Blessing, et al. The Oncogenic Helicase ALC1 Regulates PARP Inhibitor Potency by Trapping PARP2 at DNA Breaks. Mol Cell. 2020 Dec 3;80(5):862-875.e6. [Content Brief]
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