1. Biology Dictionary
  2. Cleavage and polyadenylation specificity factor subunit 4

Cleavage and polyadenylation specificity factor subunit 4

Definition:

Component of the cleavage and polyadenylation specificity factor (CPSF) complex that play a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A) polymerase and other factors to bring about cleavage and poly(A) addition. CPSF4 binds RNA polymers with a preference for poly(U).

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