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COLO-679

Definition:

COLO-679 is a human cancer cell line derived from Soft tissue and associated with Cutaneous melanoma. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. COLO-679 is used as an in vitro model of Cutaneous melanoma to investigate cytotoxicity.

References:

[1]. Anestopoulos I, et al. Isothiocyanates Enhance the Anti-Melanoma Effect of Zebularine Through Modulation of Apoptosis and Regulation of DNMTs' Expression, Chromatin Configuration and Histone Posttranslational Modifications Associated with Altered Gene Expression Patterns. Epigenomes. 2025;9(1).

[2]. Czyżowska A, et al. The cell membrane as the barrier in the defense against nanoxenobiotics: Zinc oxide nanoparticles interactions with native and model membrane of melanoma cells. Journal of applied toxicology : JAT. 2022;42(2):334-341.

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