Covalent inhibitor

Definition:

Covalent inhibitor is a kind of compound that can form a covalent bond with a specific target.Covalent inhibitors increases the duration of interaction with its target, and thereby avoiding off-target toxicity.

References:

[1]. CovalSutanto F,et al. Covalent inhibitors: a rational approach to drug discovery. RSC Med Chem. 2020 Jul 2;11(8):876-884. ent inhibitors: a rational approach to drug discovery. [Content Brief]

Biomedical Dictionary

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