Cytotoxic T lymphocytes (CTLs)

Definition:

Cytotoxic T lymphocytes (CTLs) is a kind of cells with potent defences against virus infection and intracellular pathogens. CTLs are also related to diseases by inhibiting self-tissues in autoimmune disorders, transplanted cells during graft rejection and host tissues to cause graft-versus-host disease.

References:

[1]. Barry M, et al. Cytotoxic T lymphocytes: all roads lead to death. Nat Rev Immunol. 2002 Jun;2(6):401-9. [Content Brief]

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