Double-strand break repair protein MRE11
Definition:
References:
-
[1]. M de Jager, et al. Human Rad50/Mre11 is a flexible complex that can tether DNA ends. Mol Cell. 2001 Nov;8(5):1129-35. [Content Brief]
[2]. Flavie Coquel, et al. SAMHD1 acts at stalled replication forks to prevent interferon induction. Nature. 2018 May;557(7703):57-61. [Content Brief]
[3]. Ji-Hoon Lee, et al. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science. 2004 Apr 2;304(5667):93-6. [Content Brief]
[4]. X D Zhu, et al. Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres. Nat Genet. 2000 Jul;25(3):347-52. [Content Brief]
[5]. T T Paull, et al. The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. Mol Cell. 1998 Jun;1(7):969-79. [Content Brief]
[6]. Ron D Jachimowicz, et al. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 2019 Jan 24;176(3):505-519.e22. [Content Brief]
[7]. K M Trujillo, et al. Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95. J Biol Chem. 1998 Aug 21;273(34):21447-50. [Content Brief]
[8]. J P Carney, et al. The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response. Cell. 1998 May 1;93(3):477-86. [Content Brief]
Molarity Calculator
Dilution Calculator
