1. Biology Dictionary
  2. E3 ubiquitin-protein ligase DTX4

E3 ubiquitin-protein ligase DTX4

Definition:

Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations (By similarity). Functions as a ubiquitin ligase protein in vivo, mediating 'Lys48'-linked polyubiquitination and promoting degradation of TBK1, targeting to TBK1 requires interaction with NLRP4.

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