Extracellular signal-regulated kinase (ERK)

Definition:

Extracellular signal-regulated kinase (ERK) is a member of the mitogen-activated protein kinase family of signaling molecules. ERK is predominantly found in two forms, ERK1 (p44) and ERK2 (p42), respectively. There are also several atypical forms of ERK, including ERK3, ERK4, ERK5 and ERK7. The ERK1/2 signaling pathway has been implicated in many and diverse cellular events, including proliferation, growth, differentiation, cell migration, cell survival, metabolism and transcription.

References:

[1]. Yuzhen Niu, et al. Current developments in extracellular-regulated protein kinase (ERK1/2) inhibitors. Drug Discov Today. 2022 May;27(5):1464-1473. [Content Brief]

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