Gamma-aminobutyric acid receptor subunit beta-3
Definition:
References:
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[1]. Paul S Miller, et al. Crystal structure of a human GABAA receptor. Nature. 2014 Aug 21;512(7514):270-5. [Content Brief]
[2]. Vaishali S Janve, et al. Epileptic encephalopathy de novo GABRB mutations impair γ-aminobutyric acid type A receptor function. Ann Neurol. 2016 May;79(5):806-825. [Content Brief]
[3]. Arunesh Saras, et al. Histamine action on vertebrate GABAA receptors: direct channel gating and potentiation of GABA responses. J Biol Chem. 2008 Apr 18;283(16):10470-5. [Content Brief]
[4]. Miyabi Tanaka, et al. Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy. Am J Hum Genet. 2008 Jun;82(6):1249-61. [Content Brief]
[5]. Laura E Brown, et al. Inhibitory synapse formation in a co-culture model incorporating GABAergic medium spiny neurons and HEK293 cells stably expressing GABAA receptors. J Vis Exp. 2014 Nov 14;(93):e52115. [Content Brief]
[6]. David C Chiara, et al. Mapping general anesthetic binding site(s) in human α1β3 γ-aminobutyric acid type A receptors with [³H]TDBzl-etomidate, a photoreactive etomidate analogue. Biochemistry. 2012 Jan 31;51(4):836-47. [Content Brief]
[7]. Katharine N Gurba, et al. GABRB3 mutation, G32R, associated with childhood absence epilepsy alters α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor expression and channel gating. J Biol Chem. 2012 Apr 6;287(15):12083-97. [Content Brief]
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