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H69AR

Definition:

H69AR is a human cancer cell line derived from Pleural effusion and associated with Lung small cell carcinoma and Small cell lung cancer. H69AR is a resistant derivative of NCI-H69 selected against Adriamycin. H69AR is used as an in vitro model of Lung small cell carcinoma and Small cell lung cancer to investigate drug resistance.

References:

[1]. Salido M, et al. Cytogenetic characterization of NCI-H69 and NCI-H69AR small cell lung cancer cell lines by spectral karyotyping. Cancer genetics and cytogenetics. 2009;191(2):97-101.

[2]. Loo CY, et al. Evaluation of curcumin nanoparticles of various sizes for targeting multidrug-resistant lung cancer cells via inhalation. Nanomedicine (London, England). 2025;20(2):141-153.

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