Hapten (Half Antigen)

Definition:

Hapten (Half Antigen), also known as incomplete antigen, only have immunoreactivity (antigenicity) but not immunogenicity. Hapten (Half Antigen) induces by cross-linking or binding to carriers of macromolecular proteins or nonantigenic poly-lysine to mmune responses.

References:

[1]. Erkes DA, et al. Hapten-induced contact hypersensitivity, autoimmune reactions, and tumor regression: plausibility of mediating antitumor immunity. J Immunol Res. 2014;2014:175265. [Content Brief]

[2]. Marini S, et al. A simple method for increasing hapten immunogenicity by a specific structural modification of the carrier. J Immunol Methods. 1989 Jun 2;120(1):57-63. [Content Brief]

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