Hepatitis C

Definition:

Hepatitis C is a blood-borne infectious disease caused by Hepatitis C virus (HCV) belonging to the Flaviviridae family of +ssRNA viruses. HCV infection often becomes chronic and can lead to degenerative liver diseases including fibrosis and cirrhosis. Some of these may eventually lead to hepatocellular carcinoma.

References:

[1]. C Goulding, et al. The CCR5-delta32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source. Gut. 2005 Aug;54(8):1157-61. [Content Brief]

[2]. Mei-Hsuan Lee, et al. Epidemiology and natural history of hepatitis C virus infection. World J Gastroenterol. 2014 Jul 28;20(28):9270-80. [Content Brief]

[3]. R Dawes, et al. Altered CD45 expression in C77G carriers influences immune function and outcome of hepatitis C infection. J Med Genet. 2006 Aug;43(8):678-84. [Content Brief]

[4]. Shilpa Lingala, et al. Natural History of Hepatitis C. Gastroenterol Clin North Am. 2015 Dec;44(4):717-34. [Content Brief]

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