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HepG2/Adm

Definition:

HepG2/Adm is a human cancer cell line derived from Liver and associated with Hepatoblastoma. HepG2/Adm is a resistant derivative of Hep-G2 selected against Adriamycin. HepG2/Adm is used as an in vitro model of Hepatoblastoma to investigate drug resistance.

References:

[1]. Ye RP, Chen ZD. Saikosaponin A, an active glycoside from Radix bupleuri, reverses P-glycoprotein-mediated multidrug resistance in MCF-7/ADR cells and HepG2/ADM cells. Xenobiotica; the fate of foreign compounds in biological systems. 2017;47(2):176-184.

[2]. Sun H, et al. The cycloartane triterpenoid ADCX impairs autophagic degradation through Akt overactivation and promotes apoptotic cell death in multidrug-resistant HepG2/ADM cells. Biochemical pharmacology. 2017;146:87-100.

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

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