Histone-lysine N-methyltransferase MECOM
Definition:
References:
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[1]. S Chakraborty, et al. Interaction of EVI1 with cAMP-responsive element-binding protein-binding protein (CBP) and p300/CBP-associated factor (P/CAF) results in reversible acetylation of EVI1 and in co-localization in nuclear speckles. J Biol Chem. 2001 Nov 30;276(48):44936-43. [Content Brief]
[2]. M Kurokawa, et al. The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3. Nature. 1998 Jul 2;394(6688):92-6. [Content Brief]
[3]. M Shimabe, et al. Pbx1 is a downstream target of Evi-1 in hematopoietic stem/progenitors and leukemic cells. Oncogene. 2009 Dec 10;28(49):4364-74. [Content Brief]
[4]. M Kurokawa, et al. The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death. EMBO J. 2000 Jun 15;19(12):2958-68. [Content Brief]
[5]. Eriko Nitta, et al. Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP. Oncogene. 2005 Sep 8;24(40):6165-73. [Content Brief]
[6]. Y Liu, et al. Evi1 is a survival factor which conveys resistance to both TGFbeta- and taxol-mediated cell death via PI3K/AKT. Oncogene. 2006 Jun 15;25(25):3565-75. [Content Brief]
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