Humanin

[1]. Kenzo Terashita, et al. Two serine residues distinctly regulate the rescue function of Humanin, an inhibiting factor of Alzheimer's disease-related neurotoxicity: functional potentiation by isomerization and dimerization. J Neurochem. 2003 Jun;85(6):1521-38. [Content Brief]

[2]. Yuichi Hashimoto, et al. Apollon/Bruce is upregulated by Humanin. Mol Cell Biochem. 2014 Dec;397(1-2):147-55. [Content Brief]

[3]. Radhika H Muzumdar, et al. Humanin: a novel central regulator of peripheral insulin action. PLoS One. 2009 Jul 22;4(7):e6334. [Content Brief]

[4]. Bin Guo, et al. Humanin peptide suppresses apoptosis by interfering with Bax activation. Nature. 2003 May 22;423(6938):456-61. [Content Brief]

[5]. Dayong Zhai, et al. Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak. J Biol Chem. 2005 Apr 22;280(16):15815-24. [Content Brief]

[6]. Qingqing Qin, et al. Humanin promotes mitochondrial biogenesis in pancreatic MIN6 β-cells. Biochem Biophys Res Commun. 2018 Feb 26;497(1):292-297. [Content Brief]

[7]. Masataka Harada, et al. N-Formylated humanin activates both formyl peptide receptor-like 1 and 2. Biochem Biophys Res Commun. 2004 Nov 5;324(1):255-61. [Content Brief]

[8]. Xiaohui Wang, et al. Humanin prevents high glucose-induced monocyte adhesion to endothelial cells by targeting KLF2. Mol Immunol. 2018 Sep;101:245-250. [Content Brief]

[9]. Andrea Caricasole, et al. A novel rat gene encoding a Humanin-like peptide endowed with broad neuroprotective activity. FASEB J. 2002 Aug;16(10):1331-3. [Content Brief]

[10]. Margherita Romeo, et al. Humanin Specifically Interacts with Amyloid-β Oligomers and Counteracts Their in vivo Toxicity. J Alzheimers Dis. 2017;57(3):857-871. [Content Brief]

[11]. Frederic Luciano, et al. Cytoprotective peptide humanin binds and inhibits proapoptotic Bcl-2/Bax family protein BimEL. J Biol Chem. 2005 Apr 22;280(16):15825-35. [Content Brief]

[12]. Shen-Ting Zhao, et al. Neuroprotective Peptide humanin inhibits inflammatory response in astrocytes induced by lipopolysaccharide. Neurochem Res. 2013 Mar;38(3):581-8. [Content Brief]

[13]. Wenfeng Li, et al. Humanin Ameliorates Free Fatty Acid-Induced Endothelial Inflammation by Suppressing the NLRP3 Inflammasome. ACS Omega. 2020 Aug 26;5(35):22039-22045. [Content Brief]

[14]. Daniel L Morris, et al. Humanin selectively prevents the activation of pro-apoptotic protein BID by sequestering it into fibers. J Biol Chem. 2020 Dec 25;295(52):18226-18238. [Content Brief]

[15]. Yohichi Yamagishi, et al. Identification of essential amino acids in Humanin, a neuroprotective factor against Alzheimer's disease-relevant insults. Peptides. 2003 Apr;24(4):585-95. [Content Brief]

[16]. YanHe Lue, et al. Opposing roles of insulin-like growth factor binding protein 3 and humanin in the regulation of testicular germ cell apoptosis. Endocrinology. 2010 Jan;151(1):350-7. [Content Brief]

[17]. Y Hashimoto, et al. Detailed characterization of neuroprotection by a rescue factor humanin against various Alzheimer's disease-relevant insults. J Neurosci. 2001 Dec 1;21(23):9235-45. [Content Brief]

[18]. Evert Njomen, et al. Humanin Peptide Binds to Insulin-Like Growth Factor-Binding Protein 3 (IGFBP3) and Regulates Its Interaction with Importin-β. Protein Pept Lett. 2015;22(10):869-76. [Content Brief]

[19]. Y Hashimoto, et al. A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Abeta. Proc Natl Acad Sci U S A. 2001 May 22;98(11):6336-41. [Content Brief]

[20]. Douglas Matsunaga, et al. Humanin Protects RPE Cells from Endoplasmic Reticulum Stress-Induced Apoptosis by Upregulation of Mitochondrial Glutathione. PLoS One. 2016 Oct 26;11(10):e0165150. [Content Brief]

[21]. Guoguang Ying, et al. Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor. J Immunol. 2004 Jun 1;172(11):7078-85. [Content Brief]

[22]. Yuichi Hashimoto, et al. Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor alpha/WSX-1/gp130. Mol Biol Cell. 2009 Jun;20(12):2864-73. [Content Brief]

[23]. Nesreen Alsanousi, et al. Solution NMR structure and inhibitory effect against amyloid-β fibrillation of Humanin containing a d-isomerized serine residue. Biochem Biophys Res Commun. 2016 Sep 2;477(4):647-653. [Content Brief]

[24]. Parameswaran G Sreekumar, et al. The Mitochondrial-Derived Peptide Humanin Protects RPE Cells From Oxidative Stress, Senescence, and Mitochondrial Dysfunction. Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1238-53. [Content Brief]

[25]. Maaria Ikonen, et al. Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):13042-7. [Content Brief]

[26]. Daniel L Morris, et al. Humanin induces conformational changes in the apoptosis regulator BAX and sequesters it into fibers, preventing mitochondrial outer-membrane permeabilization. J Biol Chem. 2019 Dec 13;294(50):19055-19065. [Content Brief]