Iduronate 2-sulfatase

Definition:

Lysosomal enzyme involved in the degradation pathway of dermatan sulfate and heparan sulfate.

References:

[1]. Mykhaylo Demydchuk, et al. Insights into Hunter syndrome from the structure of iduronate-2-sulfatase. Nat Commun. 2017 Jun 8;8:15786. [Content Brief]

[2]. G R Villani, et al. Expression of five iduronate-2-sulfatase site-directed mutations. Biochim Biophys Acta. 2000 Jun 15;1501(2-3):71-80. [Content Brief]

[3]. G Bonuccelli, et al. The effect of four mutations on the expression of iduronate-2-sulfatase in mucopolysaccharidosis type II. Biochim Biophys Acta. 2001 Nov 29;1537(3):233-8. [Content Brief]

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