JEG-3
Definition:
JEG-3 is a human cancer cell line derived from Fetal brain and associated with Gestational choriocarcinoma. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. JEG-3 is used as an in vitro model of Gestational choriocarcinoma to investigate cell differentiation.
References:
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[1]. Mikhailova V, et al. JEG-3 Trophoblast Cells Influence ILC-like Transformation of NK Cells In Vitro. International journal of molecular sciences. 2025;26(8). [Content Brief]
[2]. Huang YS, et al. Long-term subculture induces syncytialization and influent the response to bisphenol A (BPA) of placental JEG-3 cells. Reproductive toxicology (Elmsford, N.Y.). 2024;130:108738. [Content Brief]
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