JeKo-1
Definition:
JeKo-1 is a human cancer cell line derived from Peripheral blood and associated with Mantle cell lymphoma. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. JeKo-1 is used as an in vitro model of Mantle cell lymphoma to investigate autophagy and drug resistance.
References:
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[1]. Li G, et al. TriBAFF-CAR-T cells eliminate B-cell malignancies with BAFFR-expression and CD19 antigen loss. Cancer cell international. 2021;21(1):223. [Content Brief]
[2]. Zhang L, et al. S100A8 promotes chemoresistance via augmenting autophagy in B‑cell lymphoma cells. Oncology reports. 2021;45(1):151-158. [Content Brief]
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