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L132

Definition:

L132 is a human cancer cell line derived from Uterus, cervix and associated with Human papillomavirus-related endocervical adenocarcinoma. L132 is immortalized or transformed by Human papillomavirus type 18 (HPV18). L132 is used as an in vitro model of Human papillomavirus-related endocervical adenocarcinoma to investigate apoptosis, mitochondrial function, and nanoparticle uptake and toxicity.

References:

[1]. Koslowski R, et al. Apoptosis and release of CD44s in bleomycin-treated L132 cells. Journal of cellular biochemistry. 2005;95(6):1146-56.

[2]. Gurunathan S, et al. Multidimensional effects of biologically synthesized silver nanoparticles in Helicobacter pylori, Helicobacter felis, and human lung (L132) and lung carcinoma A549 cells. Nanoscale research letters. 2015;10:35.

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