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LX-2

Definition:

LX-2 is a human Hepatic stellate cell transformed cell line derived from Liver. LX-2 is immortalized or transformed by Simian virus 40 (SV40). LX-2 is used to investigate pyroptosis and cell differentiation in a controlled cellular system.

References:

[1]. Lin H, et al. Emerging Alternaria Toxins Drive LX-2 Cells Transdifferentiation into Myofibroblasts for Liver Fibrosis and CotA Detoxification. Journal of agricultural and food chemistry. 2026;74(16):13162-13178. [Content Brief]

[2]. Zhang M, Li L, Li S. The Role of miR-150-5p/SOCS1 Pathway in Arsenic-Induced Pyroptosis of LX-2 Cells. Biological trace element research. 2025;203(2):822-834.

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