Mastermind-like protein 3
Definition:
Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1.
References:
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[1]. Lizi Wu, et al. Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors. Mol Cell Biol. 2002 Nov;22(21):7688-700. [Content Brief]
[2]. Sey-En Lin, et al. Identification of new human mastermind proteins defines a family that consists of positive regulators for notch signaling. J Biol Chem. 2002 Dec 27;277(52):50612-20. [Content Brief]
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