MDA-MB-435S
Definition:
MDA-MB-435S is a human cancer cell line derived from Right buttock, hypodermis and associated with Amelanotic melanoma. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. MDA-MB-435S is used as an in vitro model of Amelanotic melanoma to investigate tumor-cell growth, cell survival, and pharmacological response.
References:
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[1]. Ellison G, et al. Further evidence to support the melanocytic origin of MDA-MB-435. Molecular pathology : MP. 2002;55(5):294-9. [Content Brief]
[2]. Frixen UH, et al. E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells. The Journal of cell biology. 1991;113(1):173-85. [Content Brief]
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