MDA-MB-453
Definition:
MDA-MB-453 is a human cancer cell line derived from Pericardial effusion and associated with Breast adenocarcinoma. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. MDA-MB-453 is used as an in vitro model of Breast adenocarcinoma to investigate apoptosis, cell proliferation, cell-cycle control, and gene-expression regulation.
References:
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[1]. Meng J, et al. Effects of hirsuteine on MDA-MB-453 breast cancer cell proliferation. Oncology letters. 2023;25(1):4. [Content Brief]
[2]. Alsafadi DB, et al. The Association of RGS2 and Slug in the Androgen-induced Acquisition of Mesenchymal Features of Breast MDA-MB-453 Cancer Cells. Endocrine research. 2022;47(2):64-79. [Content Brief]
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