MIT domain-containing protein 1

Definition:

Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex.

References:

[1]. Seongju Lee, et al. MITD1 is recruited to midbodies by ESCRT-III and participates in cytokinesis. Mol Biol Cell. 2012 Nov;23(22):4347-61. [Content Brief]

[2]. Michael A Hadders, et al. ESCRT-III binding protein MITD1 is involved in cytokinesis and has an unanticipated PLD fold that binds membranes. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17424-9. [Content Brief]

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