MOLM-14
Definition:
MOLM-14 is a human cancer cell line derived from Peripheral blood and associated with Adult acute myeloid leukemia and Acute myeloid leukemia. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. MOLM-14 is used as an in vitro model of Adult acute myeloid leukemia and Acute myeloid leukemia to investigate tumor-cell growth, cell survival, and pharmacological response.
References:
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[1]. Matsuo Y, et al. Two acute monocytic leukemia (AML-M5a) cell lines (MOLM-13 and MOLM-14) with interclonal phenotypic heterogeneity showing MLL-AF9 fusion resulting from an occult chromosome insertion, ins(11;9)(q23;p22p23). Leukemia. 1997;11(9):1469-77. [Content Brief]
[2]. Quentmeier H, et al. FLT3 mutations in acute myeloid leukemia cell lines. Leukemia. 2003;17(1):120-4. [Content Brief]
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