MOLT-4

Definition:

MOLT-4 is a human T-cell-derived cancer cell line derived from Peripheral blood and associated with Adult T acute lymphoblastic leukemia and Precursor T-cell acute lymphoblastic leukemia. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. MOLT-4 is used as an in vitro model of Adult T acute lymphoblastic leukemia and Precursor T-cell acute lymphoblastic leukemia to investigate p53 signaling and gene-expression regulation.

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