NCI-H209
Definition:
NCI-H209 is a human cancer cell line derived from Bone marrow and associated with Lung small cell carcinoma and Small cell lung cancer. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. NCI-H209 is used as an in vitro model of Lung small cell carcinoma and Small cell lung cancer to investigate apoptosis, cell proliferation, and cell migration.
References:
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[1]. Liu X, et al. Knockdown of neuron-specific enolase suppresses the proliferation and migration of NCI-H209 cells. Oncology letters. 2019;18(5):4809-4815. [Content Brief]
[2]. Wang Y, et al. Single-patient single-cell RNA sequencing reveals neuroendocrine predominance and immunosuppression in small-cell lung cancer. Translational cancer research. 2026;15(1):46. [Content Brief]
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