Nuclear factor E2-related factor 2 (Nrf2)

Definition:

Nuclear factor E2-related Factor-2 (Nrf2), is a key transcription factor that regulates cellular redox homeostasis, has been reported to play both protective and pathogenic roles depending on the disease conditions through undefined mechanism.

References:

[1]. Zhao C, et al. Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation. J Biol Chem. 2014 Jun 13;289(24):17020-9. [Content Brief]

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