Pfeiffer
Definition:
Pfeiffer is a human B-cell-derived cancer cell line derived from Pleural effusion and associated with Diffuse large B-cell lymphoma germinal center B-cell type and Diffuse large B-cell lymphoma. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. Pfeiffer is used as an in vitro model of Diffuse large B-cell lymphoma germinal center B-cell type and Diffuse large B-cell lymphoma to investigate mTOR signaling, autophagy, and cell proliferation.
References:
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[1]. Han J, et al. Antitumor effects and mechanisms of 1,25(OH)2D3 in the Pfeiffer diffuse large B lymphoma cell line. Molecular medicine reports. 2019;20(6):5064-5074. [Content Brief]
[2]. McAlack RF, et al. Vibriolytic antibody-forming cells: a new application of the Pfeiffer phenomenon. Science (New York, N.Y.). 1970;168(3927):141-2. [Content Brief]
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