Poly [ADP-ribose] polymerase 2

[1]. Juan José Bonfiglio, et al. Serine ADP-Ribosylation Depends on HPF1. Mol Cell. 2017 Mar 2;65(5):932-940.e6. [Content Brief]

[2]. Sejal Vyas, et al. Family-wide analysis of poly(ADP-ribose) polymerase activity. Nat Commun. 2014 Jul 21;5:4426. [Content Brief]

[3]. Qian Chen, et al. PARP2 mediates branched poly ADP-ribosylation in response to DNA damage. Nat Commun. 2018 Aug 13;9(1):3233. [Content Brief]

[4]. Silvija Bilokapic, et al. Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin. Nature. 2020 Sep;585(7826):609-613. [Content Brief]

[5]. Ezeogo Obaji, et al. Structural basis for DNA break recognition by ARTD2/PARP2. Nucleic Acids Res. 2018 Dec 14;46(22):12154-12165. [Content Brief]

[6]. Tatyana A Kurgina, et al. Dual function of HPF1 in the modulation of PARP1 and PARP2 activities. Commun Biol. 2021 Nov 3;4(1):1259. [Content Brief]

[7]. J C Amé, et al. PARP-2, A novel mammalian DNA damage-dependent poly(ADP-ribose) polymerase. J Biol Chem. 1999 Jun 18;274(25):17860-8. [Content Brief]

[8]. Jugal Mohapatra, et al. Serine ADP-ribosylation marks nucleosomes for ALC1-dependent chromatin remodeling. Elife. 2021 Dec 7;10:e71502. [Content Brief]

[9]. Luka Bacic, et al. Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome. Elife. 2021 Sep 6;10:e71420. [Content Brief]

[10]. Marcin J Suskiewicz, et al. HPF1 completes the PARP active site for DNA damage-induced ADP-ribosylation. Nature. 2020 Mar;579(7800):598-602. [Content Brief]

[11]. Ezeogo Obaji, et al. Activation of PARP2/ARTD2 by DNA damage induces conformational changes relieving enzyme autoinhibition. Nat Commun. 2021 Jun 9;12(1):3479. [Content Brief]

[12]. Ibtissam Talhaoui, et al. Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro. Nucleic Acids Res. 2016 Nov 2;44(19):9279-9295. [Content Brief]

[13]. Marie-France Langelier, et al. HPF1 dynamically controls the PARP1/2 balance between initiating and elongating ADP-ribose modifications. Nat Commun. 2021 Nov 18;12(1):6675. [Content Brief]

[14]. Gabriella Zarkovic, et al. Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation. Nucleic Acids Res. 2018 Mar 16;46(5):2417-2431. [Content Brief]