Polycystic kidney disease 2-like 1 protein
Definition:
References:
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[1]. Raymond E Hulse, et al. Cryo-EM structure of the polycystin 2-l1 ion channel. Elife. 2018 Jul 13;7:e36931. [Content Brief]
[2]. Yong Yu, et al. Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex. Nat Commun. 2012;3:1252. [Content Brief]
[3]. Wang Zheng, et al. A novel PKD2L1 C-terminal domain critical for trimerization and channel function. Sci Rep. 2015 Mar 30;5:9460. [Content Brief]
[4]. X Z Chen, et al. Polycystin-L is a calcium-regulated cation channel permeable to calcium ions. Nature. 1999 Sep 23;401(6751):383-6. [Content Brief]
[5]. Paul G DeCaen, et al. Direct recording and molecular identification of the calcium channel of primary cilia. Nature. 2013 Dec 12;504(7479):315-8. [Content Brief]
[6]. Wang Zheng, et al. Regulation of TRPP3 Channel Function by N-terminal Domain Palmitoylation and Phosphorylation. J Biol Chem. 2016 Dec 2;291(49):25678-25691. [Content Brief]
[7]. Qiang Li, et al. The calcium-binding EF-hand in polycystin-L is not a domain for channel activation and ensuing inactivation. FEBS Lett. 2002 Apr 10;516(1-3):270-8. [Content Brief]
[8]. Wang Zheng, et al. Direct Binding between Pre-S1 and TRP-like Domains in TRPP Channels Mediates Gating and Functional Regulation by PIP2. Cell Rep. 2018 Feb 6;22(6):1560-1573. [Content Brief]
[9]. Taufiqul Huque, et al. Sour ageusia in two individuals implicates ion channels of the ASIC and PKD families in human sour taste perception at the anterior tongue. PLoS One. 2009 Oct 8;4(10):e7347. [Content Brief]