Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1
Definition:
References:
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[1]. Chia-Hsueh Lee, et al. Structures of the Human HCN1 Hyperpolarization-Activated Channel. Cell. 2017 Jan 12;168(1-2):111-120.e11. [Content Brief]
[2]. Catherine H Gill, et al. Characterization of the human HCN1 channel and its inhibition by capsazepine. Br J Pharmacol. 2004 Oct;143(3):411-21. [Content Brief]
[3]. Carla Marini, et al. HCN1 mutation spectrum: from neonatal epileptic encephalopathy to benign generalized epilepsy and beyond. Brain. 2018 Nov 1;141(11):3160-3178. [Content Brief]
[4]. Mattia Bonzanni, et al. A novel de novo HCN1 loss-of-function mutation in genetic generalized epilepsy causing increased neuronal excitability. Neurobiol Dis. 2018 Oct;118:55-63. [Content Brief]