Prion-like protein doppel
Definition:
Required for normal acrosome reaction and for normal male fertility (By similarity). Can bind Cu(2+).
References:
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[1]. Diego La Mendola, et al. A doppel alpha-helix peptide fragment mimics the copper(II) interactions with the whole protein. Chemistry. 2010 Jun 1;16(21):6212-23. [Content Brief]
[2]. Grazia M Cereghetti, et al. Copper(II) binding to the human Doppel protein may mark its functional diversity from the prion protein. J Biol Chem. 2004 Aug 27;279(35):36497-503. [Content Brief]
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