Protein NPAT
Definition:
References:
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[1]. J Zhao, et al. Expression of NPAT, a novel substrate of cyclin E-CDK2, promotes S-phase entry. Genes Dev. 1998 Feb 15;12(4):456-61. [Content Brief]
[2]. Guang Gao, et al. NPAT expression is regulated by E2F and is essential for cell cycle progression. Mol Cell Biol. 2003 Apr;23(8):2821-33. [Content Brief]
[3]. Aiyan Wang, et al. Dynamic interaction of p220(NPAT) and CBP/p300 promotes S-phase entry. Biochem Biophys Res Commun. 2004 Dec 24;325(4):1509-16. [Content Brief]
[4]. Ricardo Medina, et al. The HiNF-P/p220NPAT cell cycle signaling pathway controls nonhistone target genes. Cancer Res. 2007 Nov 1;67(21):10334-42. [Content Brief]
[5]. J Zhao, et al. NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription. Genes Dev. 2000 Sep 15;14(18):2283-97. [Content Brief]
[6]. Partha Mitra, et al. HiNF-P is a bifunctional regulator of cell cycle controlled histone H4 gene transcription. J Cell Biochem. 2007 May 1;101(1):181-91. [Content Brief]
[7]. Partha Mitra, et al. Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase. Mol Cell Biol. 2003 Nov;23(22):8110-23. [Content Brief]
[8]. T Ma, et al. Cell cycle-regulated phosphorylation of p220(NPAT) by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription. Genes Dev. 2000 Sep 15;14(18):2298-313. [Content Brief]
[9]. Yue Wei, et al. The cyclin E/Cdk2 substrate and Cajal body component p220(NPAT) activates histone transcription through a novel LisH-like domain. Mol Cell Biol. 2003 May;23(10):3669-80. [Content Brief]
[10]. Angela Miele, et al. HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition. Mol Cell Biol. 2005 Jul;25(14):6140-53. [Content Brief]
[11]. Xin Ye, et al. The cyclin E/Cdk2 substrate p220(NPAT) is required for S-phase entry, histone gene expression, and Cajal body maintenance in human somatic cells. Mol Cell Biol. 2003 Dec;23(23):8586-600. [Content Brief]
[12]. William F Holmes, et al. Coordinate control and selective expression of the full complement of replication-dependent histone H4 genes in normal and cancer cells. J Biol Chem. 2005 Nov 11;280(45):37400-7. [Content Brief]
[13]. Michael DeRan, et al. Transcriptional activation of histone genes requires NPAT-dependent recruitment of TRRAP-Tip60 complex to histone promoters during the G1/S phase transition. Mol Cell Biol. 2008 Jan;28(1):435-47. [Content Brief]
[14]. Rong-Lin Xie, et al. Transcriptional activation of the histone nuclear factor P (HiNF-P) gene by HiNF-P and its cyclin E/CDK2 responsive co-factor p220NPAT defines a novel autoregulatory loop at the G1/S phase transition. Gene. 2007 Nov 1;402(1-2):94-102. [Content Brief]