Proton-coupled zinc antiporter SLC30A5
Definition:
References:
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[1]. Ehud Ohana, et al. Identification of the Zn2+ binding site and mode of operation of a mammalian Zn2+ transporter. J Biol Chem. 2009 Jun 26;284(26):17677-86. [Content Brief]
[2]. Ruth A Cragg, et al. A novel zinc-regulated human zinc transporter, hZTL1, is localized to the enterocyte apical membrane. J Biol Chem. 2002 Jun 21;277(25):22789-97. [Content Brief]
[3]. Ruth A Valentine, et al. ZnT5 variant B is a bidirectional zinc transporter and mediates zinc uptake in human intestinal Caco-2 cells. J Biol Chem. 2007 May 11;282(19):14389-93. [Content Brief]
[4]. Kaori Ishihara, et al. Zinc transport complexes contribute to the homeostatic maintenance of secretory pathway function in vertebrate cells. J Biol Chem. 2006 Jun 30;281(26):17743-50. [Content Brief]
[5]. Takumi Wagatsuma, et al. Zinc transport via ZNT5-6 and ZNT7 is critical for cell surface glycosylphosphatidylinositol-anchored protein expression. J Biol Chem. 2022 Jun;298(6):102011. [Content Brief]
[6]. Eitan Hoch, et al. Histidine pairing at the metal transport site of mammalian ZnT transporters controls Zn2+ over Cd2+ selectivity. Proc Natl Acad Sci U S A. 2012 May 8;109(19):7202-7. [Content Brief]
[7]. Taiho Kambe, et al. Cloning and characterization of a novel mammalian zinc transporter, zinc transporter 5, abundantly expressed in pancreatic beta cells. J Biol Chem. 2002 May 24;277(21):19049-55. [Content Brief]
[8]. Tomoyuki Suzuki, et al. Two different zinc transport complexes of cation diffusion facilitator proteins localized in the secretory pathway operate to activate alkaline phosphatases in vertebrate cells. J Biol Chem. 2005 Sep 2;280(35):30956-62. [Content Brief]
[9]. Tomoyuki Suzuki, et al. Zinc transporters, ZnT5 and ZnT7, are required for the activation of alkaline phosphatases, zinc-requiring enzymes that are glycosylphosphatidylinositol-anchored to the cytoplasmic membrane. J Biol Chem. 2005 Jan 7;280(1):637-43. [Content Brief]