Rab11 family-interacting protein 5

Definition:

Rab effector involved in protein trafficking from apical recycling endosomes to the apical plasma membrane. Involved in insulin granule exocytosis. May regulate V-ATPase intracellular transport in response to extracellular acidosis.

References:

[1]. R Prekeris, et al. A Rab11/Rip11 protein complex regulates apical membrane trafficking via recycling endosomes. Mol Cell. 2000 Dec;6(6):1437-48. [Content Brief]

[2]. Oliver Oehlke, et al. Rab11b and its effector Rip11 regulate the acidosis-induced traffic of V-ATPase in salivary ducts. J Cell Physiol. 2011 Mar;226(3):638-51. [Content Brief]

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