Retinal guanylyl cyclase 1
Definition:
References:
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[1]. C L Tucker, et al. Two amino acid substitutions convert a guanylyl cyclase, RetGC-1, into an adenylyl cyclase. Proc Natl Acad Sci U S A. 1998 May 26;95(11):5993-7. [Content Brief]
[2]. Hanna Wimberg, et al. Photoreceptor Guanylate Cyclase ( GUCY2D) Mutations Cause Retinal Dystrophies by Severe Malfunction of Ca2+-Dependent Cyclic GMP Synthesis. Front Mol Neurosci. 2018 Sep 25;11:348. [Content Brief]
[3]. Igor V Peshenko, et al. Retinal degeneration 3 (RD3) protein inhibits catalytic activity of retinal membrane guanylyl cyclase (RetGC) and its stimulation by activating proteins. Biochemistry. 2011 Nov 8;50(44):9511-9. [Content Brief]
[4]. Igor V Peshenko, et al. Dimerization Domain of Retinal Membrane Guanylyl Cyclase 1 (RetGC1) Is an Essential Part of Guanylyl Cyclase-activating Protein (GCAP) Binding Interface. J Biol Chem. 2015 Aug 7;290(32):19584-96. [Content Brief]
[5]. Chandra L Tucker, et al. Functional analyses of mutant recessive GUCY2D alleles identified in Leber congenital amaurosis patients: protein domain comparisons and dominant negative effects. Mol Vis. 2004 Apr 20;10:297-303. [Content Brief]
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