Sclerostin

Definition:

Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.

References:

[1]. Mikhail Semënov, et al. SOST is a ligand for LRP5/LRP6 and a Wnt signaling inhibitor. J Biol Chem. 2005 Jul 22;280(29):26770-5. [Content Brief]

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