Secreted aspartic protease 2 (SAP2)

Definition:

Secreted aspartic protease 2 (SAP2) is a secreted enzyme essential for C. albicans growth in a protein-rich environment that cleaves peptide bonds between hydrophobic amino acids.

References:

[1]. Svoboda E, et al. Secreted aspartic protease 2 of Candida albicans inactivates factor H and the macrophage factor H-receptors CR3 (CD11b/CD18) and CR4 (CD11c/CD18). Immunol Lett. 2015 Nov;168(1):13-21. [Content Brief]

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