Septin-14

Definition:

Filament-forming cytoskeletal GTPase (Probable). Involved in the migration of cortical neurons and the formation of neuron leading processes during embryonic development (By similarity). Plays a role in sperm head formation during spermiogenesis, potentially via facilitating localization of ACTN4 to cell filaments.

References:

[1]. Yu-Hua Lin, et al. ACTN4 Mediates SEPT14 Mutation-Induced Sperm Head Defects. Biomedicines. 2020 Nov 19;8(11):518. [Content Brief]

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