Serine protease inhibitor Kazal-type 6
Definition:
Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit KLK8.
References:
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[1]. Tomasz Kantyka, et al. Inhibition of kallikrein-related peptidases by the serine protease inhibitor of Kazal-type 6. Peptides. 2011 Jun;32(6):1187-92. [Content Brief]
[2]. Ulf Meyer-Hoffert, et al. Isolation of SPINK6 in human skin: selective inhibitor of kallikrein-related peptidases. J Biol Chem. 2010 Oct 15;285(42):32174-81. [Content Brief]
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