Serine-protein kinase ATM

[1]. Bo Qin, et al. UFL1 promotes histone H4 ufmylation and ATM activation. Nat Commun. 2019 Mar 18;10(1):1242. [Content Brief]

[2]. D S Lim, et al. ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. Nature. 2000 Apr 6;404(6778):613-7. [Content Brief]

[3]. S Banin, et al. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science. 1998 Sep 11;281(5383):1674-7. [Content Brief]

[4]. M Gatei, et al. ATM-dependent phosphorylation of nibrin in response to radiation exposure. Nat Genet. 2000 May;25(1):115-9. [Content Brief]

[5]. Sergei V Kozlov, et al. Involvement of novel autophosphorylation sites in ATM activation. EMBO J. 2006 Aug 9;25(15):3504-14. [Content Brief]

[6]. Ambereen Ali, et al. Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation. Genes Dev. 2004 Feb 1;18(3):249-54. [Content Brief]

[7]. K K Khanna, et al. ATM associates with and phosphorylates p53: mapping the region of interaction. Nat Genet. 1998 Dec;20(4):398-400. [Content Brief]

[8]. C E Canman, et al. Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science. 1998 Sep 11;281(5383):1677-9. [Content Brief]

[9]. Jiangwei Zhang, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015 Oct;17(10):1259-1269. [Content Brief]

[10]. S Li, et al. Functional link of BRCA1 and ataxia telangiectasia gene product in DNA damage response. Nature. 2000 Jul 13;406(6792):210-5. [Content Brief]

[11]. Constantinos Demonacos, et al. A new effector pathway links ATM kinase with the DNA damage response. Nat Cell Biol. 2004 Oct;6(10):968-76. [Content Brief]

[12]. Anindita Bhoumik, et al. ATM-dependent phosphorylation of ATF2 is required for the DNA damage response. Mol Cell. 2005 May 27;18(5):577-87. [Content Brief]

[13]. Toshiyasu Taniguchi, et al. Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. Cell. 2002 May 17;109(4):459-72. [Content Brief]

[14]. Yingli Sun, et al. DNA damage-induced acetylation of lysine 3016 of ATM activates ATM kinase activity. Mol Cell Biol. 2007 Dec;27(24):8502-9. [Content Brief]

[15]. Qiang Zhang, et al. FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4. Mol Cell. 2016 Feb 4;61(3):419-433. [Content Brief]

[16]. Giancarlo Barone, et al. Modeling ATM mutant proteins from missense changes confirms retained kinase activity. Hum Mutat. 2009 Aug;30(8):1222-30. [Content Brief]

[17]. S Matsuoka, et al. Ataxia telangiectasia-mutated phosphorylates Chk2 in vivo and in vitro. Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10389-94. [Content Brief]

[18]. X Wu, et al. ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature. 2000 May 25;405(6785):477-82. [Content Brief]

[19]. Ron D Jachimowicz, et al. UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors. Cell. 2019 Jan 24;176(3):505-519.e22. [Content Brief]

[20]. Nicole L Batenburg, et al. ATM and CDK2 control chromatin remodeler CSB to inhibit RIF1 in DSB repair pathway choice. Nat Commun. 2017 Dec 4;8(1):1921. [Content Brief]

[21]. S Kishi, et al. Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks. J Biol Chem. 2001 Aug 3;276(31):29282-91. [Content Brief]

[22]. Handan Kaygun, et al. Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1. Nat Struct Mol Biol. 2005 Sep;12(9):794-800. [Content Brief]

[23]. D Cortez, et al. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science. 1999 Nov 5;286(5442):1162-6. [Content Brief]

[24]. Christopher J Bakkenist, et al. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature. 2003 Jan 30;421(6922):499-506. [Content Brief]

[25]. Naoe Taira, et al. ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage. J Biol Chem. 2010 Feb 12;285(7):4909-19. [Content Brief]

[26]. Xiaoshan Zhang, et al. Artemis is a phosphorylation target of ATM and ATR and is involved in the G2/M DNA damage checkpoint response. Mol Cell Biol. 2004 Oct;24(20):9207-20. [Content Brief]