Serine/threonine-protein kinase 4

[1]. Hyun Jung Oh, et al. Role of the tumor suppressor RASSF1A in Mst1-mediated apoptosis. Cancer Res. 2006 Mar 1;66(5):2562-9. [Content Brief]

[2]. W N Cooper, et al. RASSF2 associates with and stabilizes the proapoptotic kinase MST2. Oncogene. 2009 Aug 20;28(33):2988-98. [Content Brief]

[3]. Bei You, et al. Phosphorylation of cardiac troponin I by mammalian sterile 20-like kinase 1. Biochem J. 2009 Feb 15;418(1):93-101. [Content Brief]

[4]. Fang Yuan, et al. MST1 promotes apoptosis through regulating Sirt1-dependent p53 deacetylation. J Biol Chem. 2011 Mar 4;286(9):6940-5. [Content Brief]

[5]. Maria Praskova, et al. MOBKL1A/MOBKL1B phosphorylation by MST1 and MST2 inhibits cell proliferation. Curr Biol. 2008 Mar 11;18(5):311-21. [Content Brief]

[6]. Bekir Cinar, et al. MST1 is a multifunctional caspase-independent inhibitor of androgenic signaling. Cancer Res. 2011 Jun 15;71(12):4303-13. [Content Brief]

[7]. C L Creasy, et al. The Ste20-like protein kinase, Mst1, dimerizes and contains an inhibitory domain. J Biol Chem. 1996 Aug 30;271(35):21049-53. [Content Brief]

[8]. L K Taylor, et al. Newly identified stress-responsive protein kinases, Krs-1 and Krs-2. Proc Natl Acad Sci U S A. 1996 Sep 17;93(19):10099-104. [Content Brief]

[9]. Wang L Cheung, et al. Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase. Cell. 2003 May 16;113(4):507-17. [Content Brief]

[10]. Bekir Cinar, et al. The pro-apoptotic kinase Mst1 and its caspase cleavage products are direct inhibitors of Akt1. EMBO J. 2007 Oct 31;26(21):4523-34. [Content Brief]

[11]. S Ura, et al. Caspase cleavage of MST1 promotes nuclear translocation and chromatin condensation. Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10148-53. [Content Brief]

[12]. Karel Valis, et al. Hippo/Mst1 stimulates transcription of the proapoptotic mediator NOXA in a FoxO1-dependent manner. Cancer Res. 2011 Feb 1;71(3):946-54. [Content Brief]

[13]. Maria K Lehtinen, et al. A conserved MST-FOXO signaling pathway mediates oxidative-stress responses and extends life span. Cell. 2006 Jun 2;125(5):987-1001. [Content Brief]

[14]. K K Lee, et al. MST, a physiological caspase substrate, highly sensitizes apoptosis both upstream and downstream of caspase activation. J Biol Chem. 2001 Jun 1;276(22):19276-85. [Content Brief]

[15]. Maria Praskova, et al. Regulation of the MST1 kinase by autophosphorylation, by the growth inhibitory proteins, RASSF1 and NORE1, and by Ras. Biochem J. 2004 Jul 15;381(Pt 2):453-62. [Content Brief]

[16]. Bernard A Callus, et al. Association of mammalian sterile twenty kinases, Mst1 and Mst2, with hSalvador via C-terminal coiled-coil domains, leads to its stabilization and phosphorylation. FEBS J. 2006 Sep;273(18):4264-76. [Content Brief]