Serpin B11

Definition:

Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change.

References:

[1]. David J Askew, et al. SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change. J Biol Chem. 2007 Aug 24;282(34):24948-60. [Content Brief]

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