Serpin B8

Definition:

Has an important role in epithelial desmosome-mediated cell-cell adhesion.

References:

[1]. Manuela Pigors, et al. Loss-of-Function Mutations in SERPINB8 Linked to Exfoliative Ichthyosis with Impaired Mechanical Stability of Intercellular Adhesions. Am J Hum Genet. 2016 Aug 4;99(2):430-6. [Content Brief]

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