Sideroflexin-2

Definition:

Mitochondrial amino-acid transporter that mediates transport of serine into mitochondria. Involved in mitochondrial iron homeostasis by regulating heme biosynthesis.

References:

[1]. Ei Ei Mon, et al. Regulation of mitochondrial iron homeostasis by sideroflexin 2. J Physiol Sci. 2019 Mar;69(2):359-373. [Content Brief]

[2]. Nora Kory, et al. SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism. Science. 2018 Nov 16;362(6416):eaat9528. [Content Brief]

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