Small interfering RNA (siRNA)

Definition:

Small-interfering RNA (siRNA), synthetic double-stranded RNA consisting of approximately 21 base pairs, suppresses problematic target genes in a sequence-specific manner via inherent RNA interference (RNAi) processing. As a result, siRNA offers a potential strategy for treatment of many human diseases.

References:

[1]. Lee SH, et al. Small-interfering RNA (siRNA)-based functional micro- and nanostructures for efficient and selective gene silencing. Acc Chem Res. 2012 Jul 17;45(7):1014-25. [Content Brief]

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