Somatostatin

Definition:

Somatostatin, also known as growth hormone-inhibiting hormone (GHIH), is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of numerous secondary hormones. Somatostatin inhibits insulin and glucagon secretion.

References:

[1]. Costanzi E, et al. Two neuroendocrine G protein-coupled receptor molecules, somatostatin and melatonin: Physiology of signal transduction and therapeutic perspectives. J Cell Physiol. 2021 Apr;236(4):2505-2518. [Content Brief]

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