Sulfotransferase 1E1
Definition:
References:
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[1]. Ian T Cook, et al. 24-hydroxycholesterol sulfation by human cytosolic sulfotransferases: formation of monosulfates and disulfates, molecular modeling, sulfatase sensitivity, and inhibition of liver x receptor activation. Drug Metab Dispos. 2009 Oct;37(10):2069-78. [Content Brief]
[2]. Brittany D Needham, et al. A gut-derived metabolite alters brain activity and anxiety behaviour in mice. Nature. 2022 Feb;602(7898):647-653. [Content Brief]
[3]. C N Falany, et al. Bacterial expression and characterization of a cDNA for human liver estrogen sulfotransferase. J Steroid Biochem Mol Biol. 1995 Jun;52(6):529-39. [Content Brief]
[4]. N Hempel, et al. Site-directed mutagenesis of the substrate-binding cleft of human estrogen sulfotransferase. Biochem Biophys Res Commun. 2000 Sep 16;276(1):224-30. [Content Brief]
[5]. Lars C Pedersen, et al. Crystal structure of the human estrogen sulfotransferase-PAPS complex: evidence for catalytic role of Ser137 in the sulfuryl transfer reaction. J Biol Chem. 2002 May 17;277(20):17928-32. [Content Brief]
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